2,3-Dihydro-1H-indol-6-ylboronic acid, pinacol ester
Boronic acid, B-(2,3-dihydro-1H-indol-6-yl)-
CAS: 1253912-15-0
Molecular Formula: C8H10BNO2
2,3-Dihydro-1H-indol-6-ylboronic acid, pinacol ester - Names and Identifiers
2,3-Dihydro-1H-indol-6-ylboronic acid, pinacol ester - Physico-chemical Properties
| Molecular Formula | C8H10BNO2 |
| Molar Mass | 162.98 |
| Density | 1.27±0.1 g/cm3(Predicted) |
| Boling Point | 371.8±52.0 °C(Predicted) |
| pKa | 8.88±0.20(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Sensitive | Irritant |
| MDL | MFCD18383472 |
2,3-Dihydro-1H-indol-6-ylboronic acid, pinacol ester - Introduction
B- (2,3-Dihydro-1H-indol-6-yl)-boronic acid pinacol ester is an organic compound with the following properties:
1. Appearance: The common B- (2,3-dihydro-1H-indol-6-yl)-boronic acid pinacol ester is a white crystalline solid.
2. Solubility: It has good solubility in some common organic solvents, such as methanol, ethanol and ether solvents.
3. Stability: Under normal temperature and pressure, it is relatively stable and has good chemical stability.
The main use of B- (2,3-dihydro-1H-indol-6-yl)-boronic acid pinacol ester is as a catalyst in organic synthesis, especially in important carbon-nitrogen bond and carbon-carbon bond construction reactions. It can promote the reaction of organic compounds, improve the reaction speed and product yield.
The method for preparing B- (2,3-dihydro-1H-indol-6-yl)-boronic acid pinacol ester is generally by reacting pyrrole and boronic acid pinacol ester under alkaline conditions to carry out esterification reaction. This preparation step is carried out under an inert atmosphere to avoid the possibility of air oxidation and hydrolysis.
Regarding safety information, B- (2,3-dihydro-1H-indol-6-yl)-boronic acid pinacol ester is relatively safe under normal operating conditions, but the following matters still need to be noted:
1. Avoid inhalation: During operation, avoid inhaling dust or gas.
2. Avoid skin contact: Wear appropriate personal protective equipment, such as gloves and lab coats, to avoid skin contact.
3. pay attention to the source of fire: due to the characteristics of organic compounds, avoid contact with open flame, high temperature or strong oxidant.
4. storage and handling: B- (2,3-dihydro-1H-indol-6-yl)-boronic acid pinacol ester should be stored in a sealed container, in a cool, dry place away from fire and oxide.
When using this compound, it is recommended to refer to the relevant safety data sheet and operating manual to ensure safe operation.
1. Appearance: The common B- (2,3-dihydro-1H-indol-6-yl)-boronic acid pinacol ester is a white crystalline solid.
2. Solubility: It has good solubility in some common organic solvents, such as methanol, ethanol and ether solvents.
3. Stability: Under normal temperature and pressure, it is relatively stable and has good chemical stability.
The main use of B- (2,3-dihydro-1H-indol-6-yl)-boronic acid pinacol ester is as a catalyst in organic synthesis, especially in important carbon-nitrogen bond and carbon-carbon bond construction reactions. It can promote the reaction of organic compounds, improve the reaction speed and product yield.
The method for preparing B- (2,3-dihydro-1H-indol-6-yl)-boronic acid pinacol ester is generally by reacting pyrrole and boronic acid pinacol ester under alkaline conditions to carry out esterification reaction. This preparation step is carried out under an inert atmosphere to avoid the possibility of air oxidation and hydrolysis.
Regarding safety information, B- (2,3-dihydro-1H-indol-6-yl)-boronic acid pinacol ester is relatively safe under normal operating conditions, but the following matters still need to be noted:
1. Avoid inhalation: During operation, avoid inhaling dust or gas.
2. Avoid skin contact: Wear appropriate personal protective equipment, such as gloves and lab coats, to avoid skin contact.
3. pay attention to the source of fire: due to the characteristics of organic compounds, avoid contact with open flame, high temperature or strong oxidant.
4. storage and handling: B- (2,3-dihydro-1H-indol-6-yl)-boronic acid pinacol ester should be stored in a sealed container, in a cool, dry place away from fire and oxide.
When using this compound, it is recommended to refer to the relevant safety data sheet and operating manual to ensure safe operation.
Last Update：2024-04-09 21:21:28
